The Denver Broncos' first loss under rookie coach Josh McDaniels produced plenty of problems that need fixing and one big injury they'll have to deal with.

McDaniels said right tackle Ryan Harris won't play against Pittsburgh next week after sustaining a toe injury in the Broncos' loss at Baltimore. McDaniels was still trying to learn the extent of Harris' injury.

Harris, a third-year pro from Notre Dame, has started 22 consecutive games for one of the league's best offensive lines. He was replaced in the first half Sunday by second-year pro Tyler Polumbus, who is in line to make his first NFL start against the Steelers next Monday night.