About 250 Fort Carson soldiers deployed Friday, leaving from the Colorado Jet Center.
Most of them are among more than 5,000 3rd Armored Cavalry Regiment soldiers, heading to the Middle East within a 3 week span.
For many, it's a return trip to parts of Iraq and Kuwait, just about a year after coming home. They're expected to be gone for about a year.
47 Fort Carson soldiers have been killed since the war started.