SAN DIEGO (AP) - Gerardo Parra hit a go-ahead, three-run homer in the sixth inning and rookie Noel Cuevas went deep for the first time as the Colorado Rockies beat the San Diego Padres 6-4 Monday night.
Daniel Castro also homered for the Rockies, who won for the second time in six games.
Franmil Reyes made his big league debut for the Padres after leading all of professional baseball in homers with 14 while at Triple-A El Paso. He started in right field and went 0 for 4. He reached on a throwing error by shortstop Trevor Story that allowed Franchy Cordero to score for a 2-1 lead in the fourth.
Freddy Galvis of the Padres finished a homer short of the cycle. Colorado's Nolan Arenado had three hits and an RBI.
Tyler Anderson (3-1) allowed four runs, three earned, on seven hits in 5 2/3 innings and reached base twice against rookie lefty Joey Lucchesi. Anderson walked with one out in the third and scored on Arenado's single. He singled in the fifth before being forced out.
Wade Davis pitched the ninth for his 15th save.
Parra gave the Rockies a 6-3 lead when he connected with one out in the sixth off Kazuhisa Makita (0-1), who was making his first appearance since being recalled from Triple-A on Sunday. Parra's second homer of the season came with Ian Desmond and Chris Iannetta aboard on singles.
Castro homered leading off the fifth, his first, and Cuevas connected with two outs for a 3-2 lead. Cuevas made his major league debut on April 22.
Lucchesi struggled through five innings, allowing three runs and six hits while striking out two and walking one. He also was thrown out trying to score on a passed ball to end the third. The big pitcher lumbered down the line and an awkward slide left him short of the plate.
Rockies: Placed All-Star second baseman DJ LeMahieu on the 10-day disabled list with a sprained left thumb and recalled infielder Pat Valaika from Triple-A Albuquerque. LeMahieu was hurt Sunday while taking a swing during a loss to Milwaukee. He was batting .279 with five home runs and 13 RBIs.
Rockies: RHP German Marquez (2-4, 5.35 ERA) is scheduled to pitch the finale of the two-game series. He tossed three innings against San Diego on April 11 in Denver before being ejected for his part in a brawl that started when San Diego's Luis Perdomo threw behind Arenado.
Padres: RHP Jordan Lyles (0-1, 3.28) will start against his former team.
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